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Control of force steadiness and accuracy after stroke

  • Objective: Describe changes in force steadiness and accuracy from subacute to chronic stage of stroke in relation to motor impairment; determine effects of different training paradigms and interventions on force steadiness and accuracy
  • Lead Investigator: John W. Chow, PhD
  • Related Publications: Chow JW, Stokic DS, force, stroke – Search Results – PubMed
  • Funding: The Wilson Research Foundation, Jackson, MS

Lower Limb Flexor Synergy Training in Chronic Stroke

Shared and distinct antispastic effects of electrical and pharmacological neuromodulation

Transcutaneous spinal stimulation for reducing lower limb spasticity in chronic spinal cord injury

  • Objective: To determine if electrical neuromodulation can reduce muscle stiffness and spasms in people with spinal cord injury in a home-based therapy setting.
  • Lead Investigator: Matthias J. Krenn, Ph.D.
  • Related Publications: New
  • Funding: Paralyzed Veterans of America
  • Detailed information: click here
  • Status: RECRUITING. If you are interested in participating, click here​

Electrical neuromodulation for modifying the spinal network involved in spasticity

Neurophysiologic investigation of inter-limb connectivity after SCI

  • Objective: Investigate residual connectivity between upper and lower limbs in complete SCI
  • Lead Investigator: Dobrivoje S. Stokic, MD, DSc
  • Related Publications: New
  • Funding: The Wilson Research Foundation, Jackson, MS
  • Status: Recruiting, if interested to participate, click here

Effect of pulse characteristics used for transcutaneous spinal stimulation on short-latency responses in lower limb muscles

Defining the capacity of the lumbosacral network for neuromodulation in humans with spinal cord injury

  • Objective: To determine how electrical neuromodulation affects the responsiveness of the lumbosacral network in people with spinal cord injuries. We aim to understand how spinal reflexes can demonstrate the potential for neuromodulation at different stimulation intensities and frequencies.
  • Principal Investigator: Matthias J. Krenn, Ph.D.
  • Related Publications: New
  • Funding: Wings for Life USA – Spinal Cord Research Foundation Inc.
  • Detailed information: click here
  • Status: Closed

Characteristics of gait in patients with moderate-to-severe muscle hypertonia after acquired brain injury

  • Objective: To describe changes in gait parameters and muscle activation patterns in patients with moderate-to-severe hypertonia after acquired brain injury
  • Investigators: John W. Chow, Ph.D.
  • Outside Collaborator: Stuart A. Yablon, M.D., Department of Physical Medicine and Rehabilitation, UT Southwestern Health Science Center, Dallas, TX
  • Related Publications:
  • Funding: The Wilson Research Foundation, Jackson, MS
  • Status: Retrospective study (not recruiting)

Peripheral nervous system injury after traumatic brain injury

  • Objective: Describe prevalence and types of EMG confirmed peripheral nervous system injuries among patients admitted to inpatient rehabilitation for traumatic brain injury
  • Lead Investigator: Art Leis, M.D.
  • Outside Collaborators: Stuart A. Yablon, MD, Department of Physical Medicine and Rehabilitation, UT Southwestern Health Science Center, Dallas, TX
  • Related Publications: In Progress
  • Funding: The Wilson Research Foundation, Jackson, MS
  • Status: Retrospective study (not recruiting)

The utility of soleus H-reflex for monitoring and troubleshooting intrathecal baclofen administration

  • Objective: Determine how serial recordings of soleus H-reflex can help determine adequate or inadequate delivery of intrathecal baclofen for control of spasticity
  • Lead Investigator: Dobrivoje S. Stokic, M.D., D.Sc.
  • Outside Collaborator: Stuart A. Yablon, M.D., Department of Physical Medicine and Rehabilitation, UT Southwestern Health Science Center, Dallas, TX
  • Related Publications:
  • Funding: The Wilson Research Foundation, Jackson, MS
  • Status: Recruiting internally (not open to public)

Complications of the implantable drug delivery system for intrathecal administration of baclofen for control of spasticity after acquired brain injury

  • Objective: Determine prevalence and types of system malfunctions among the recipients of intrathecal baclofen pump for control of spasticity
  • Principal Investigator: Dobrivoje S. Stokic, M.D., D.Sc. 
  • Outside Collaborators: Stuart A. Yablon, M.D., Department of Physical Medicine and Rehabilitation, UT Southwestern Health Science Center, Dallas, TX
  • Related Publications:
  • Funding: The Wilson Research Foundation, Jackson, MS
  • Status: Retrospective study (not recruiting)

Characteristics of gait in patients with moderate-to-severe muscle hypertonia after acquired brain injury

  • Objective: To describe changes in gait parameters and muscle activation patterns in patients with moderate-to-severe hypertonia after acquired brain injury
  • Lead Investigator: John W. Chow, Ph.D.
  • Outside Collaborator: Stuart A. Yablon, M.D., Department of Physical Medicine and Rehabilitation, UT Southwestern Health Science Center, Dallas, TX
  • Related Publications:
  • Funding: The Wilson Research Foundation, Jackson, MS
  • Status: Retrospective study (not recruiting)

Effect of intrathecal baclofen on gait in patients with muscle hypertonia after acquired brain injury

  • Objective: Describe changes in gait and muscle activation patterns after bolus or continuous intrathecal baclofen administration for control of spasticity after acquired brain injury
  • Lead Investigator: John W. Chow, Ph.D.
  • Outside Collaborator: Stuart A. Yablon, M.D., Department of Physical Medicine and Rehabilitation, UT Southwestern Health Science Center, Dallas, TX
  • Related Publications:
  • Funding: The Wilson Research Foundation, Jackson, MS
  • Status: Recruiting internally (not open to public)

Characteristics of the strength-duration profiles of short-latency responses evoked by transcutaneous spinal stimulation